"What is a gene? The gene concept faced to recent advances in genetics, molecular and developmental biology."
1 : Université Pierre et Marie Curie - Paris 6
(UPMC)
-
Website
Université Paris VI - Pierre et Marie Curie
4 place Jussieu - 75005 Paris -
France
SourceURL:file://localhost/Users/jeandeutsch/Documents/Conf%C3%A9rences%202013/Mtpellier/What%20is%20a%20gene.doc The molecular concept of the gene, defined during the 1960s as a continuous segment of coding DNA has been faced to several drawbacks: the discovery of introns and the use of alternative promoters, the amount of non-coding regulatory signals, small and large regulatory non-coding RNAs, and last but not least, cell- and generation-transmitted epigenetics.